Potential Antiepileptic Activity of Spirulina: The Concept of Antioxident Properties in Rats Model of epilepsy

Abstract

Blue-green algae, or Spirulina platensis, is used as a dietary supplement. It has a high protein content, antioxidants, several phytopigments, and neuroprotective properties. Penzyltetrazole is one of the greatest medications for creating an animal model of epilepsy, which is recognized as a neuropsychiatric condition in humans with a shortened lifespan and deficits in social and professional functioning. While many antiepileptic medications are recognized as effective treatments for epilepsy symptoms, they also have negative side effects. As a result, the need for novel therapies or treatments with minimal side effects is overwhelming. By giving spirulina to rat groups following seizure induction and comparing the results with those of valporic acid, the antioxidant impact of spirulina was investigated. Taking spirulina by itself and When spirulina is administered both alone and in conjunction with an antiepileptic medication, oxidative stress indicators such as MDA that are generated by PTZ induction decrease.